Off-Label Drug Use In Pediatrics Assignment help – Discussion 3

The unapproved use of approved drugs, also called off-label use, with children is quite common. This is because pediatric dosage guidelines are typically unavailable since very few drugs have been specifically researched and tested with children.

When treating children, prescribers often adjust dosages approved for adults to accommodate a child’s weight. However, children are not just “smaller” adults. Adults and children process and respond to drugs differently in their absorption, distribution, metabolism, and excretion. Children even respond differently during stages from infancy to adolescence. This poses potential safety concerns when prescribing drugs to pediatric patients. As an advanced practice nurse, you have to be aware of safety implications of the off-label use of drugs with this patient group.

To prepare:

· Review the Panther et al (2017) and Corney, Lebel, Bailey, and Bussieres (2015) articles in the Learning Resources. Reflect on situations in which children should be prescribed drugs for off-label use.

· Think about strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence. Consider specific off-label drugs that you think require extra care and attention when used in pediatrics.

With these thoughts in mind:

Homework help – Write Include sub headings plz. And purpose of writing.

· an explanation of circumstances under which children should be prescribed drugs for off-label use.

· Then, describe strategies to make the off-label use and dosage of drugs safer for children from infancy to adolescence.

· Include descriptions and names of off-label drugs that require extra care and attention when used in pediatrics.

Points to follow when writing a paper:

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You must proofread your paper. But do not strictly rely on your computer’s spell-checker and grammar-checker; failure to do so indicates a lack of effort on your part and you can expect your grade to suffer accordingly. Papers with numerous misspelled words and grammatical mistakes will be penalized. Read over your paper – in silence and then aloud – before handing it in and make corrections as necessary. Often it is advantageous to have a friend proofread your paper for obvious errors. Handwritten corrections are preferable to uncorrected mistakes.

Use a standard 10 to 12 point (10 to 12 characters per inch) typeface. Smaller or compressed type and papers with small margins or single-spacing are hard to read. It is better to let your essay run over the recommended number of pages than to try to compress it into fewer pages.

Likewise, large type, large margins, large indentations, triple-spacing, increased leading (space between lines), increased kerning (space between letters), and any other such attempts at “padding” to increase the length of a paper are unacceptable, wasteful of trees, and will not fool your professor.

The paper must be neatly formatted, double-spaced with a one-inch margin on the top, bottom, and sides of each page. When submitting hard copy, be sure to use white paper and print out using dark ink. If it is hard to read your essay, it will also be hard to follow your argument.
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Assignment help – Discussion 3: Off-Label Pediatric Drugs

Off-label usage of licensed medications in children is extremely widespread. It’s because very few medications have been specially investigated and tested on youngsters.

Prescribers often adapt adult dosages for youngsters based on their weight. But kids aren’t merely “smaller” grownups. Drug absorption, distribution, metabolism, and excretion varies between adults and children. From infancy through adolescence, children respond differently. This may constitute a risk when providing medications to children. As an APRN, you must be aware of the risks associated with off-label drug usage in this patient population.

Prep:

Re-read Panther et al (2017) and Corney et al (2015) in the Learning Resources. Consider when children should be provided off-label medications.

Consider ways to make off-label drug use and dosage safer for children from birth to puberty. Consider off-label medications that you believe deserve particular caution in children.

Keeping in mind:

Please include subheadings. And writing purpose.

a description of when children should be provided off-label medications.

Define safe off-label drug use and dose for children from infancy to puberty.

List off-label medications that demand special caution when used in children.

Guidelines for drafting a paper:

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Proofread your work. Dependence on your computer’s spell- and grammar-checker implies a lack of effort on your behalf, and your grade will suffer accordingly. Mispelled words and grammatical errors will be fined. Before submitting your paper, read it aloud and in silence, making any required adjustments. It helps to have a buddy proofread your writing for obvious mistakes. Handwritten corrections beat uncorrected errors.

Use a 10-12 point typeface (10-12 characters per inch). Smaller type, narrow margins, and single-spaced articles are difficult to read. It is best to let your essay go above the recommended page count than to attempt and squeeze it in.

Increased leading (space between lines), kerning (space between letters) and any other such attempts to “padding” a paper are improper, waste trees, and will not trick your professor.

The paper must be double-spaced with a one-inch margin on all sides. If submitting a hard copy, utilize white paper and dark ink. Reading your essay will make it difficult to follow your reasoning.

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