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Posted: January 17th, 2023

Advanced Patho Week 5 Homework help – Discussion 2 Responses-Anaphylactic Shock

Response #1 to I
Great post on Anaphylactic shock Rahab, you provided great content and wrote about an important patient factor of behavior having an impact on this medical emergency. Behavior is an important factor in preventing anaphylactic shock. An individual who has experienced anaphylaxis needs to develop an emergency action plan, keep more than one EpiPen on hand and use it at the first signs of symptoms, avoid the allergen responsible for the episode, and continue follow-up care with a primary care clinician or allergist (Campbell & Kelso, 2018). It is important for the patient to know how to inject with the EpiPen, it is imperative for the ARNP to make sure the patient is successfully able to inject themselves. Patient education on anaphylactic shock reduces the risk of recurrence (Campbell & Kelso, 2018).

Campbell, R. L., & Kelso, J. M. (2018). Anaphylaxis: Acute diagnosis. Retrieved from
https://www.uptodate.com/contents/anaphylaxis-acute-diagnosis

Response #2 to T
Great post on anaphylaxis Jason. I found the factor you chose very interesting, I was not aware that genetics played that big of a role in anaphylaxis. Anaphylaxis is a type 1 hypersensitivity reaction involving IgE-mediated release of histamine, leukotrienes, and other mediators from already sensitized mast cells (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). Systemic corticosteroids may help prevent late phase reactions in some cases of anaphylaxis, although it takes 4-6 hours to take effect (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). In genetically predisposed patients, allergens produce a vigorous humoral response (type 1 hypersensitivity reaction) that results in the production of large amounts of IgE antibody (Huether & McCance, 2017).

Arcangelo, V. P., Peterson, A. M., Wilbur, V., & Reinhold, J. A. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.
Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

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