Care Hope College
AP202 Lab Chap 19
Instructor: Dr. Gesner Cesar
Name:_____________________________________
Please go to Evolve Elsevier –go to your Anatomy and Physiology bookStudents Resources Chapter 19 Mechanism of diseases,
Summarize briefly these topics and provide a short definition of the following subsequent important medical term or diseases.
I-Disorders Associated with Lymphatic Vessels
a) Lymphedema
b) Elephantiasis
c) Lymphangitis,
d) Necrosis
e) Abscesses
f) Septicemia
II-Disorders Associated with Lymph Nodes and Other Lymphatic Organs
III-Lymphoma Definition and difference between:
a) Hodgkin lymphoma (HL) and
b) Non-Hodgkin lymphoma (NHL
IV-Hypersensitivity of the Immune system
a) Hypersensitivity Allergy
b) Allergens
c) Urticaria
d) Anaphylactic shock.
e) Antihistamines
f) Contact dermatitis,
g) Hypoallergenic
V-Autoimmunity
Autoimmune diseases Definition and 3 examples
VI-Isoimmunity
a) Isoimmunity
b) erythroblastosis fetalis.
c) Graves disease
d) Myasthenia gravis.
e) Tissue or organ transplants
f) Rejection syndrome
g) Human leukocyte antigens (HLAs)
VII-Difference Host-versus-graft rejection vs Graft-versus-host rejection
VIII-Immune deficiency
a) Severe combined immune deficiency (SCID)
b) Acquired immune deficiency syndrome (AIDS).
c) Human immunodeficiency virus (HIV).
d) Pneumocystis jiroveci pneumoniae
e) Kaposi sarcoma
f) Highly active antiretroviral therapy (HAART).
IX-Immunity and Cancer
Tumor-specific antigens- Definition
Tumor markers definition and the association to type of cancers
(1) Carcinoibryonic antigen (CEA)
(2) Alpha-fetoprotein (AFP
(3) CA-125
(4) Prostate-specific antigen (PSA)
X-Complete the table of Examples of Autoimmune Diseases
DISEASE
POSSIBLE SELF-ANTIGEN
DESCRIPTION
Addison disease
Surface antigens on adrenal cells
Cardiomyopathy
Disease of cardiac muscle (i.e., the myocardium), resulting in loss of pumping efficiency (heart failure)
Diabetes mellitus (type 1)
Pancreatic islet cells, insulin, insulin receptors
Glomerulonephritis
Disease of the filtration apparatus of the kidney (renal corpuscle), resulting in fluid and electrolyte imbalance and possibly total kidney failure and death
Graves disease (type of hyperthyroidism)
TSH receptors on thyroid cells
Hemolytic anemia
Condition of low RBC count in the blood resulting from excessive destruction of mature RBCs (hemolysis)
Hypothyroidism
Antigens in thyroid cells
Multiple sclerosis (MS)
Progressive degeneration of myelin sheaths, resulting in widespread impairment of nerve function (especially muscle control)
Myasthenia gravis
Antigens at neuromuscular junction
Pernicious anemia
Antigens on parietal cells, intrinsic factor
Reproductive infertility
Inability to produce offspring (in this case, resulting from destruction of gametes)
Rheumatic fever
Rheumatic heart disease; inflammatory cardiac damage (especially to the endocardium/valves)
Rheumatoid arthritis (RA)
Collagen
Systemic lupus erythematous (SLE)
Numerous
Ulcerative colitis
Chronic inflammatory disease of the colon characterized by watery diarrhea containing blood, mucus, and pus
